WATCH: Audience Boos & Walks Out After Wanda Sykes Attacks 'Racist' Donald Trump

In a Boston comedy show last night, comedian Wanda Sykes was loudly booed by large portions of the audience near the end of her set as she referred to President-elect Donald Trump as a "racist, sexist, homophobic person."

Sykes set at the Comics Come Home benefit show in the TD Garden, hosted by Dennis Leary, was pretty much an anti-Trump tirade, coming on the heels of Tuesday's shocking victory by the real estate mogul. At one point, she described Trump as an "orangutan," stating she couldn't believe the country elected him.

Throughout the majority of the set, Sykes was able to get some laughs from the crowd and didn't really face too much anger from the audience. However, near the end, when she said "this is not the first time we've elected a racist, sexist, homophobic person," many in the crowd turned on her.

Sykes, who is a black and gay, lashed back out at those booing her, pointing some out and telling them to "f*ck off." When she left the stage, she threw up a middle finger.

Then, Nick DiPaolo took the stage, unleashing a torrent of comments about liberals, Boston women, and Jews, according to attendees.

...DiPaolo drew claps and laughter for his pro-Trump rant filled with coarse language, anti-Semitic references, and jokes about raping women, they said.

“It was horrible,” said Nancy Rogerson, 47, of Framingham, who attended with Comatas. “He joked about raping women on the cobblestone streets of Boston, and people were laughing. That is not something to joke about.”

...some people were clearly unsettled by the performances.

“I’m Jewish,” said Lisa Hamblen, 58. “He called Bernie Sanders an ‘old Jew.’ He could have just called him an ‘old guy.’ ”

DiPaolo also called a woman who tried to rush the stage a “Peabody Jew,” according to the Hamblens and Rogerson. DiPaolo, who grew up in Danvers, was apparently referencing the neighboring North Shore city that has a sizable Jewish population.

“There is a fine line between comedy and hate speech,” George Hamblen said. “On the one hand, you had a very honest reaction from Wanda Sykes about what she’s going through [after the election] and she gets booed.”

DiPaolo and his booking agent, Matt Frost of Creative Artists Agency, did not respond to requests for comment from the Globe, and a representative for Sykes could not be reached.