"What I know is the truth, and the truth is I've never sexually assaulted anyone," Kavanaugh told Fox News' Martha MacCallum.
Kavanaugh's wife, Ashley, said the allegations against her husband were "hard to believe."
"I know Brett. I've known him for 17 years," she said. "He's decent, he's kind, he's good. I know his heart. This is not consistent with Brett."
California professor Christine Blasey Ford has accused Kavanaugh of covering her mouth and trying to remove her clothing at a party in the early 1980s, when both were in high school. Kavanaugh and Ford are set to testify in front of the Senate Judiciary Committee on Thursday.
In the interview, Kavanaugh emphatically denied Ford's claim against him, telling MacCallum that he was a virgin through high school and for "many years after."
"I was never at any such party," Kavanaugh said. "The other people who alleged to be present have said they do not remember any such party. A woman who was present, another woman who was present who was Dr. Ford's lifelong friend has said she doesn't know me and never remembers being at a party with me at any time in her life."
[...]"I want a fair process where I can defend my integrity, and I know I'm telling the truth," the judge said. "I know my lifelong record and I'm not going to let false accusations drive me out of this process. I have faith in God and I have faith in the fairness of the American people."
Kavanaugh also denied a New Yorker report published Sunday night in which classmate Deborah Ramirez said he exposed himself to her while they were students at Yale, pointing out that The New York Times had said it could not corroborate her claims.
"I never did any such thing," Kavanaugh said. "The other people alleged to be there don't recall any such thing. If such a thing had happened, it would have been the talk of campus."
In addition, Kavanaugh said claims by attorney Michael Avenatti that he and high school friend Mark Judge had plied women with drugs and alcohol at parties so other men could gang rape them were "totally false and outrageous."
"Yes, there were parties and the drinking age was 18 and yes, the seniors were legal and had beer there, he said. "And yes, people might have had too many beers on occasion ... I think all of us have probably done things we look back on in high school and regret or cringe a bit. But that's not what we're talking about. We're talking about an allegation of sexual assault. I've never sexually assaulted anyone."
The accusations against Kavanaugh are a complete joke but a few Republican Senators like Susan Collins and Jeff Flake are forcing this whole charade to go on.